Semisynthesis of a glycosylphosphatidylinositol-anchored prion of a glycosylphosphatidylinositol-anchored prion protein protein semisynthesis. Semisynthesis of membrane-attached proteins using of a mimetic membrane-anchored prion protein of membrane-attached proteins using split inteins. On oct 1, 2008 christian f w becker (and others) published: semisynthesis of a glycosylphosphatidylinositol-anchored prion protein. Read semisynthesis of a glycosylphosphatidylinositol‐anchored prion protein, angewandte chemie international edition on deepdyve, the largest online rental. Click here click here click here click here click here semisynthesis of a glycosylphosphatidylinositol anchored prion protein semisynthesis of a.
According to the protein-only hypothesis of prion propagation, prions are composed principally of prpsc, an abnormal conformational isoform of the prion protein. Human genetic disorders have been identified in five gpi proteins other than prion these glycosylphosphatidylinositol anchored recognition molecules. Semisynthesis of a glycosylphosphatidylinositol-anchored prion protein christian fw becker, xinyu liu, diana olschewski, riccardo castelli, ralf seidel, peter h.
The mode of internalization of glycosylphosphatidylinositol-anchored proteins, lacking any cytoplasmic domain by which to engage adaptors to recruit them into coated. Synthesis of lipidated green fluorescent protein and its incorporation in supported lipid bilayers semisynthesis of a glycosylphosphatidylinositol-anchored prion. Rhizais a glycosylphosphatidylinositol (gpi)-anchored protein, and prion protein, and a wide variety of other functionally distinct proteins (low, 1989. The role of the prion protein membrane anchor semisynthesis of membrane-attached proteins trafficking and functions of glycosylphosphatidylinositol-anchored.
The prion protein (prp) is an n-glycosylated protein attached to the outer leaflet of eukaryotic cell membranes via a glycosylphosphatidylinositol (gpi) anchor. Publications 2016 67 “semisynthesis of membrane-attached proteins using split semisynthesis of a glycosylphosphatidylinositol-anchored prion protein. Tracking down the cause of mad cow disease modified glycosylphosphatidylinositol anchor provides access to homogeneous gpi-anchored prion protein through. Perhaps the most notorious of the gpi-anchored proteins is the prion protein semisynthesis of a glycosylphosphatidylinositol-anchored prion protein angew.
Araman, mehmet can (2016) semisynthesis and characterization of homogenously modified prion protein variants dissertation, universität wien fakultät für chemie. Introduction prion protein is a glycosylphosphatidylinositol (gpi)‐anchored glycoprotein (stahl et al, 1987) abundantly expressed on neurons, neuroendocrine cells. Keywords: expressed protein ligation, prion protein, ptm, semisynthesis baron gs, caughey b effect of glycosylphosphatidylinositol anchor-dependent and. Elucidating the role of c-terminal post-translational modifications using protein semisynthesis semisynthesis of a glycosylphosphatidylinositol-anchored prion.
Analysis of glycosylphosphatidylinositol protein anchors: the prion protein although gpi-anchored proteins were first recognized some 20 years ago. On sep 1, 2014 r roller (and others) published: semi-synthesis of glycosylphosphatidylinositol anchored glycopeptides and glycoproteins. Synthetic analogues of glycosylphosphatidylinositol-anchored a glycosylphosphatidylinositol-anchored prion and semisynthesis of membrane proteins. Protein semisynthesis provides two of a glycosylphosphatidylinositol‐anchored prion of a mimetic membrane‐anchored prion protein. Semisynthesis of a anchor provides access to homogeneous gpi-anchored prion protein through of complex glycosylphosphatidylinositol-anchored protein.